Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 17/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042076 | 0.85 | MAPT (0.39) | MAPTSMPD3 | |
| SCHEMBL4042546 | 0.85 | MAPT (0.43) | MAPTSMPD3 | |
| SCHEMBL4034301 | 0.83 | GABRA1 (0.41) | MAPTSMPD3 | |
| SCHEMBL4039716 | 0.82 | ERN1 (0.43) | MAPTSMPD3 | |
| SCHEMBL4034089 | 0.82 | SMPD3 (0.46) | MAPTSMPD3 | |
| SCHEMBL4034103 | 0.81 | SMPD3 (0.40) | MAPTSMPD3 | |
| SCHEMBL15225671 | 0.81 | SMPD3 (0.40) | MAPTSMPD3 | |
| SCHEMBL4040171 | 0.81 | TUBB4A (0.41) | MAPTSMPD3 | |
| SCHEMBL4036344 | 0.78 | SMPD3 (0.41) | MAPTSMPD3 | |
| SCHEMBL1308980 | 0.77 | SMPD3 (0.40) | MAPTSMPD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066632-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | Chong Kun Dang Pharmaceutical Corp. (KR) | 2009-06-10 | — | — | EP | claimed |
| WO-2008038955-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-04-03 | — | — | WO | claimed |