Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.35 |
| ▸ | PRKACA | P17612 | 3/20 | 0.35 |
| ▸ | CDK8 | P49336 | 3/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.33 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46494 | 0.86 | — | — | |
| SCHEMBL31237159 | 0.84 | DYRK1A (0.41) | ALDH1A1GAADYRK1AMAP4K4PRKACA | |
| Hydrochloric Acid SCHEMBL30128120 | 0.84 | DYRK1A (0.41) | DYRK1AMAP4K4PRKACACDK8CLK4 | |
| Water SCHEMBL29860131 | 0.84 | DYRK1A (0.41) | DYRK1AMAP4K4PRKACACDK8CLK4 | |
| Iodide SCHEMBL9950363 | 0.84 | DYRK1A (0.41) | DYRK1AMAP4K4PRKACACDK8CLK4 | |
| SCHEMBL3962541 | 0.84 | DYRK1A (0.41) | DYRK1AMAP4K4PRKACACDK8CLK4 | |
| Urea SCHEMBL9949310 | 0.76 | KDR (0.40) | ALDH1A1MAPTDYRK1AMAP4K4PRKACA | |
| SCHEMBL102246 | 0.72 | DYRK1A (0.52) | ALDH1A1DYRK1AMAP4K4PRKACACDK8 | |
| Hydrochloric Acid SCHEMBL16372078 | 0.71 | DYRK1A (0.50) | ALDH1A1DYRK1AMAP4K4PRKACACDK8 | |
| SCHEMBL4499534 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138847-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF CEFOZOPRAN | ORCHID CHEMICALS AND PHARMACEUTICALS LTD. (IN) | 2009-11-19 | — | — | WO | disclosed |