⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962541 | 0.98 | DYRK1A (0.41) | — | |
| SCHEMBL31237159 | 0.98 | DYRK1A (0.41) | — | |
| Hydrochloric Acid SCHEMBL30128120 | 0.98 | DYRK1A (0.41) | — | |
| Water SCHEMBL29860131 | 0.98 | DYRK1A (0.41) | — | |
| Iodide SCHEMBL9950363 | 0.98 | DYRK1A (0.41) | — | |
| Urea SCHEMBL9949310 | 0.88 | KDR (0.40) | — | |
| SCHEMBL4034434 | 0.86 | ALDH1A1 (0.36) | — | |
| SCHEMBL4499534 | 0.80 | — | — | |
| SCHEMBL30752412 | 0.79 | — | — | |
| SCHEMBL18151469 | 0.78 | MAP4K4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3147 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727938-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | Prothena Biosciences Limited (IE) | 2026-04-22 | — | — | EP | claimed |
| EP-4658656-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | Beone Medicines I GmbH (CH) | 2025-12-10 | — | — | EP | claimed |
| US-20250346597-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | BEONE MEDICINES I GMBH (CH) | 2025-11-13 | — | — | US | claimed |
| US-20250333399-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | KHORA SPV 1 LLC (US) | 2025-10-30 | — | — | US | claimed |
| EP-4611899-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | Petra Pharma Corporation (US) | 2025-09-10 | — | — | EP | claimed |
| US-20250243203-A1 | NICOTINAMIDE- AND BENZAMIDE-BASED COMPOUNDS, CONJUGATES, AND COMPOSITIONS AS INHIBITORS OF TRANSLATIONAL- AND TRANSCRIPTIONAL-RELATED KINASES | PURDUE RESEARCH FOUNDATION | 2025-07-31 | — | — | US | claimed |
| CN-120118077-A | Compound and application thereof | 润尔眼科药物（广州）有限公司 | 2025-06-10 | — | — | CN | claimed |
| US-20250066318-A1 | HETEROCYCLIC COMPOUNDS AS DYRK1A INHIBITORS | PROTHENA BIOSCIENCES INC | 2025-02-27 | — | — | US | claimed |
| CN-119451675-A | Nicotinamide and benzamide based compounds, conjugates and compositions as inhibitors of translation and transcription related kinases | 普渡研究基金会 | 2025-02-14 | — | — | CN | claimed |
| EP-4504174-A2 | NICOTINAMIDE- AND BENZAMIDE-BASED COMPOUNDS, CONJUGATES, AND COMPOSITIONS AS INHIBITORS OF TRANSLATIONAL- AND TRANSCRIPTIONAL-RELATED KINASES | Purdue Research Foundation (US) | 2025-02-12 | — | — | EP | claimed |
| EP-0444549-B1 | Imidazopyridazines their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-01-25 | — | — | EP | claimed |
| EP-0238070-B1 | Sulfonylurea compounds, their production and herbicidal use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-29 | — | — | EP | claimed |
| US-5202324-A | Bronchodilators | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-04-13 | — | — | US | claimed |
| EP-0306408-B1 | Imidazo[1,2,-b]pyridazines, process for their preparation and pharmaceutical compositions containing them | ELF SANOFI (FR) | 1992-03-18 | — | — | EP | claimed |
| EP-0440119-A1 | Imidazopyridazine compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-07 | — | — | EP | claimed |
| US-5017212-A | For rice paddies | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-21 | — | — | US | claimed |
| EP-0381132-A1 | Imidazopyridazines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-08-08 | — | — | EP | claimed |
| US-4910199-A | Substituted with a phenyl ring | SANOFI (FR) | 1990-03-20 | — | — | US | claimed |
| EP-0306408-A1 | Imidazo[1,2,-b]pyridazines, process for their preparation and pharmaceutical compositions containing them | ELF SANOFI (FR) | 1989-03-08 | — | — | EP | claimed |
| EP-0238070-A2 | Sulfonylurea compounds, their production and herbicidal use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-23 | — | — | EP | claimed |