SCHEMBL102246

SCHEMBL102246

Clc1ccc2nccn2n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 4/20 0.52
KDM4E B2RXH2 3/20 0.48
CLK4 Q9HAZ1 3/20 0.46
MAPK14 Q16539 2/20 0.46
MAP4K4 O95819 2/20 0.46
PRKACA P17612 2/20 0.46
CDK8 P49336 2/20 0.46
LRRK2 Q5S007 2/20 0.46
KDR P35968 7/20 0.45
DYRK1B Q9Y463 4/20 0.45
RET P07949 3/20 0.45
JAK2 O60674 2/20 0.45
GSK3A P49840 2/20 0.45
RPS6KA3 P51812 2/20 0.45
LIMK1 P53667 2/20 0.45
MAP2K1 Q02750 2/20 0.45
ALK Q9UM73 2/20 0.45
ALDH1A1 P00352 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
PRKCI P41743 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL16372078 0.98 DYRK1A (0.50) DYRK1AKDM4ECLK4MAPK14MAP4K4
SCHEMBL3500436 0.74 DYRK1A (0.52) DYRK1ACLK4MAPK14MAP4K4PRKACA
SCHEMBL2067916 0.74 DYRK1A (0.52) DYRK1AKDM4ECLK4MAPK14MAP4K4
SCHEMBL16875635 0.74 DYRK1A (0.52) DYRK1ACLK4MAPK14MAP4K4PRKACA
SCHEMBL5487802 0.74 DYRK1A (0.52) DYRK1ACLK4MAPK14MAP4K4PRKACA
SCHEMBL7514132 0.74 DYRK1A (0.52) DYRK1ACLK4MAPK14MAP4K4PRKACA
SCHEMBL9125832 0.74 KDR (0.62) DYRK1ACLK4MAPK14MAP4K4PRKACA
SCHEMBL1051267 0.74 DYRK1A (0.52) DYRK1ACLK4MAPK14MAP4K4PRKACA
SCHEMBL4560704 0.74 DYRK1A (0.52) DYRK1ACLK4MAPK14MAP4K4PRKACA
SCHEMBL877547 0.74 DYRK1A (0.47) DYRK1ACLK4MAPK14MAP4K4PRKACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 732 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116282949-B Glass through hole copper electroplating solution for radio frequency device and copper electroplating process thereof 深圳创智芯联科技股份有限公司 2024-11-12 CN claimed
CN-116282949-A Glass through hole copper electroplating solution for radio frequency device and copper electroplating process thereof 深圳创智芯联科技股份有限公司 2023-06-23 CN claimed
EP-4719597-A1 SULFONAMIDE COMPOUNDS AS VOLTAGE-GATED CALCIUM ION CHANNEL CAV2.3 ANTAGONISTS Lario Therapeutics Limited (GB) 2026-04-08 EP disclosed
EP-4683909-A2 ATM KINASE INHIBITORS Eberhard Karls Universität Tübingen (DE) 2026-01-28 EP disclosed
US-12534469-B2 Multi-cyclic IRAK and FLT3 inhibiting compounds and uses thereof CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2026-01-27 US disclosed
US-12528810-B2 Small molecule inhibitors of DYRK/CLK and uses thereof ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2026-01-20 US disclosed
US-12528816-B2 Substituted imidazo [1,2-b] pyridazines and [1, 2, 4] triazolo [ 4,3-b] pyridazines as camkii inhibitors CARDURION PHARMACEUTICALS, INC. (US) 2026-01-20 US disclosed
US-20260015328-A1 ATM KINASE INHIBITORS EBERHARD KARLS UNIVERSITÄT TÜBINGEN (DE) 2026-01-15 US disclosed
US-12522595-B2 Bicyclic ether O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranosidase inhibitors BIOGEN MA INC. (US) 2026-01-13 US disclosed
US-20250340557-A1 PYRIMIDINE DERIVATIVE ASKA PHARMACEUTICAL CO., LTD. (JP) 2025-11-06 US disclosed
US-20250304558-A1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2025-10-02 US disclosed
EP-0381132-A1 Imidazopyridazines, their production and use Takeda Chemical Industries, Ltd. (JP) 1990-08-08 EP disclosed
US-4942159-A ANTIBIOTICS, BACTERICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-07-17 US disclosed
US-4921851-A Cephem compounds, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-05-01 US disclosed
US-4864022-A 3-Condensed imidazolium-cephem compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-09-05 US disclosed
EP-0304858-A2 Cephem compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1989-03-01 EP disclosed
EP-0249170-A2 Cephem compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1987-12-16 EP disclosed
EP-0229369-A2 Cephalosporins, process for their preparation and pharmaceutical compositions containing them Takeda Chemical Industries, Ltd. (JP) 1987-07-22 EP disclosed
EP-0203271-A2 Antibacterial compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1986-12-03 EP disclosed
WO-1986005183-A1 ANTIBACTERIAL COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1986-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528816-B2 Substituted imidazo [1,2-b] pyridazines and [1, 2, 4] triazolo [ 4,3-b] pyridazines as camkii inhibitors RYR2, CACNA1C, CAMK4 DYRK1A 1528/4885KDM4E 4364/4885CLK4 910/4885
US-12528810-B2 Small molecule inhibitors of DYRK/CLK and uses thereof CLK3, CLK2, CLK1 DYRK1A 18/4885KDM4E 2135/4885CLK4 4/4885
US-20250340557-A1 PYRIMIDINE DERIVATIVE PTGES, PTGS1, PTGIS DYRK1A 4220/4885KDM4E 3195/4885CLK4 4399/4885
US-20260015328-A1 ATM KINASE INHIBITORS ATM, CHEK2, CHEK1 DYRK1A 767/4885KDM4E 2112/4885CLK4 218/4885
US-12534469-B2 Multi-cyclic IRAK and FLT3 inhibiting compounds and uses thereof FLT3, IRAK3, IRAK2 DYRK1A 2786/4885KDM4E 607/4885CLK4 1756/4885
US-20250304558-A1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY SLC6A11, SCN1A, KCNH1 DYRK1A 3936/4885KDM4E 1095/4885CLK4 4225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.