Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038268 | 0.89 | ALDH1A1 (0.40) | ALDH1A1GAAUSP2CHRM5 | |
| SCHEMBL4033586 | 0.88 | ALDH1A1 (0.55) | ALDH1A1GAAUSP2 | |
| SCHEMBL4036877 | 0.87 | ALDH1A1 (0.52) | ALDH1A1GAAUSP2CHRM5 | |
| SCHEMBL4034695 | 0.86 | GAA (0.51) | ALDH1A1GAA | |
| SCHEMBL4036675 | 0.86 | ALDH1A1 (0.51) | ALDH1A1GAAUSP2CHRM5 | |
| SCHEMBL4035740 | 0.85 | ALDH1A1 (0.51) | ALDH1A1GAAUSP2 | |
| SCHEMBL4039378 | 0.84 | MMP1 (0.52) | ALDH1A1GAAUSP2 | |
| SCHEMBL4035627 | 0.83 | ALDH1A1 (0.48) | ALDH1A1GAAUSP2 | |
| SCHEMBL4035716 | 0.81 | ALDH1A1 (0.46) | ALDH1A1GAAUSP2 | |
| SCHEMBL4032675 | 0.80 | GAA (0.48) | ALDH1A1GAACHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |