Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033586 | 0.98 | ALDH1A1 (0.55) | ALDH1A1GAAPOLBUSP2LMNA | |
| SCHEMBL4035740 | 0.96 | ALDH1A1 (0.51) | ALDH1A1GAAPOLBUSP2LMNA | |
| SCHEMBL4039378 | 0.94 | MMP1 (0.52) | ALDH1A1GAAPOLBUSP2LMNA | |
| SCHEMBL4035627 | 0.93 | ALDH1A1 (0.48) | ALDH1A1GAAPOLBUSP2LMNA | |
| SCHEMBL4035716 | 0.93 | ALDH1A1 (0.46) | ALDH1A1GAAPOLBUSP2LMNA | |
| SCHEMBL4042256 | 0.91 | POLB (0.46) | ALDH1A1GAAPOLBUSP2LMNA | |
| SCHEMBL4034701 | 0.87 | ALDH1A1 (0.49) | ALDH1A1GAAUSP2CHRM5 | |
| SCHEMBL4034722 | 0.84 | F10 (0.46) | POLBLMNATP53CHRM5 | |
| SCHEMBL4033832 | 0.84 | MMP1 (0.49) | — | |
| SCHEMBL4033581 | 0.83 | GAA (0.57) | ALDH1A1GAAPOLBUSP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |