SCHEMBL69664

SCHEMBL69664

COC(=O)c1cccc(N=Nc2cccc(C(=O)OC)c2)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.62
MAPT P10636 3/20 0.62
CASP3 P42574 1/20 0.62
SENP8 Q96LD8 1/20 0.62
SENP7 Q9BQF6 1/20 0.62
SENP6 Q9GZR1 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
TSHR P16473 1/20 0.55
LOXL2 Q9Y4K0 1/20 0.54
CYP4F2 P78329 2/20 0.53
CYP4A11 Q02928 2/20 0.53
POLB P06746 1/20 0.51
ALDH1A1 P00352 1/20 0.50
NPC1 O15118 2/20 0.49
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 2/20 0.48
CA7 P43166 1/20 0.48
XDH P47989 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69663 1.00 RAB9A (0.62) RAB9AMAPTCASP3SENP8SENP7
SCHEMBL28393989 0.95 RAB9A (0.72) RAB9AMAPTCASP3SENP8SENP7
SCHEMBL10818316 0.95 RAB9A (0.72) RAB9AMAPTCASP3SENP8SENP7
SCHEMBL28397561 0.90 MAPT (0.53) RAB9AMAPTCASP3SENP8SENP7
SCHEMBL17572092 0.90 LOXL2 (0.53) RAB9AMAPTCASP3SENP8SENP7
Azobenzene SCHEMBL28325034 0.89 RAB9A (0.74) RAB9AMAPTCASP3SENP8SENP7
SCHEMBL28888704 0.89 RAB9A (0.59) RAB9AMAPTCASP3SENP8SENP7
SCHEMBL10160451 0.87 TSHR (0.53) RAB9AMAPTCASP3SENP8SENP7
SCHEMBL28553475 0.87 RAB9A (0.49) RAB9AMAPTCASP3SENP8SENP7
SCHEMBL40349 0.86 CYP4F2 (0.51) RAB9AMAPTCASP3SENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 RAB9A 3169/4885MAPT 1923/4885CASP3 4534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.