SCHEMBL4035912

SCHEMBL4035912

Cc1ccc([C@H]2CCCN(C(=O)O)C2)cc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MYC P01106 10/20 0.50
ACMSD Q8TDX5 2/20 0.48
PROKR1 Q8TCW9 5/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9509660 0.80 PROKR1 (0.60) PROKR1
SCHEMBL17067813 0.79 ACMSD (0.57) ACMSD
SCHEMBL4028170 0.79 PPARA (0.61) MYCPROKR1
SCHEMBL4030003 0.78 ALDH1A1 (0.47) MYCPROKR1
SCHEMBL4027831 0.78 PPARA (0.50) MYC
SCHEMBL4029181 0.78 BCL9 (0.62) MYC
SCHEMBL4029183 0.78 BCL9 (0.62) MYC
SCHEMBL29138248 0.77 QDPR (0.54) ACMSD
SCHEMBL6190079 0.77 BCL9 (0.53) PROKR1
SCHEMBL6188781 0.77 BCL9 (0.53) PROKR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1567493-B1 PHENYL SUBSTITUTED PIPERIDINE COMPOUNDS FOR USE AS PPAR ACTIVATORS PFIZER PROD INC (US) 2009-03-18 EP claimed