Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 15/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL4031589 | 0.97 | SIGMAR1 (0.65) | SIGMAR1MEN1KMT2AMCHR1CCR1 | |
| SCHEMBL6330761 | 0.85 | SIGMAR1 (0.66) | SIGMAR1MEN1KMT2ACCR1CCR3 | |
| SCHEMBL4031594 | 0.79 | SIGMAR1 (0.52) | SIGMAR1MEN1KMT2AMCHR1CCR1 | |
| SCHEMBL4032289 | 0.79 | SIGMAR1 (0.70) | SIGMAR1MEN1KMT2AMCHR1CCR1 | |
| SCHEMBL4031641 | 0.78 | POLB (0.70) | SIGMAR1MEN1KMT2AMCHR1 | |
| SCHEMBL4034910 | 0.78 | SIGMAR1 (0.66) | SIGMAR1MEN1KMT2AMCHR1CCR1 | |
| SCHEMBL12510991 | 0.77 | CCR3 (0.58) | SIGMAR1MEN1KMT2AMCHR1CCR1 | |
| SCHEMBL4033740 | 0.77 | SIGMAR1 (0.67) | SIGMAR1MEN1KMT2AMCHR1CCR1 | |
| SCHEMBL4036818 | 0.77 | SIGMAR1 (0.67) | SIGMAR1MEN1KMT2AMCHR1CCR1 | |
| Hydrochloric Acid SCHEMBL2239179 | 0.77 | CCR3 (0.58) | SIGMAR1MEN1KMT2AMCHR1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212299-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA UK LTD (GB) | 2009-04-08 | — | — | EP | claimed |