Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032585 | 0.88 | MMP1 (0.49) | CHRM1MMP1MMP9MMP13MMP3 | |
| SCHEMBL4034091 | 0.86 | GAA (0.49) | CHRM1MMP1MMP9MMP13MMP3 | |
| SCHEMBL4038753 | 0.85 | CHRM1 (0.40) | CHRM1MMP1MMP9MMP13MMP3 | |
| SCHEMBL4032608 | 0.84 | MMP1 (0.55) | CHRM1MMP1MMP9MMP13MMP3 | |
| SCHEMBL1383866 | 0.84 | GAA (0.64) | GAAMAPK1USP2TSHRHSD17B10 | |
| SCHEMBL4034484 | 0.83 | MMP1 (0.44) | CHRM1MMP1MMP9MMP13MMP3 | |
| SCHEMBL4035407 | 0.81 | MMP1 (0.51) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL4035648 | 0.76 | MMP1 (0.47) | CHRM1MMP1MMP9MMP13MMP3 | |
| SCHEMBL4035075 | 0.76 | CHRM1 (0.40) | CHRM1MMP1MMP9MMP13MMP3 | |
| SCHEMBL4041186 | 0.75 | CHRM5 (0.45) | CHRM1GAAUSP2CHRM5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |