Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CCR4 | P51679 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035075 | 0.90 | CHRM1 (0.40) | CHRM1GAAMMP1MMP3MMP7 | |
| SCHEMBL4032608 | 0.85 | MMP1 (0.55) | CHRM1GAAMMP1MMP3MMP7 | |
| SCHEMBL4036727 | 0.85 | CHRM1 (0.48) | CHRM1GAAMMP1MMP3MMP7 | |
| SCHEMBL4038343 | 0.85 | GAA (0.57) | GAAUSP2ALDH1A1 | |
| SCHEMBL4032585 | 0.84 | MMP1 (0.49) | CHRM1MMP1MMP3MMP7MMP9 | |
| SCHEMBL4034091 | 0.83 | GAA (0.49) | CHRM1GAAMMP1MMP3MMP7 | |
| SCHEMBL4035407 | 0.82 | MMP1 (0.51) | GAAMMP1MMP3MMP7MMP9 | |
| SCHEMBL4038771 | 0.81 | P2RX7 (0.45) | ALDH1A1 | |
| SCHEMBL4034484 | 0.80 | MMP1 (0.44) | CHRM1GAAMMP1MMP3MMP7 | |
| SCHEMBL4035069 | 0.75 | GAA (0.53) | GAAUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |