Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 3/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034513 | 0.93 | F10 (0.44) | CHRM5ADAM17CHRM1GBA1F2 | |
| SCHEMBL4032585 | 0.84 | MMP1 (0.49) | CHRM1CAPN1 | |
| SCHEMBL4032774 | 0.83 | GAA (0.54) | SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL4034722 | 0.81 | F10 (0.46) | CHRM5ADAM17CHRM1F2F10 | |
| SCHEMBL1381762 | 0.79 | GAA (0.49) | GAAALDH1A1 | |
| SCHEMBL4034484 | 0.78 | MMP1 (0.44) | CHRM1GAACAPN1 | |
| SCHEMBL4034091 | 0.78 | GAA (0.49) | CHRM5CHRM1SMN1; SMN2GAA | |
| SCHEMBL4036727 | 0.75 | CHRM1 (0.48) | CHRM5CHRM1SMN1; SMN2GAACAPN1 | |
| SCHEMBL4036877 | 0.74 | ALDH1A1 (0.52) | CHRM5GAAUSP2ALDH1A1 | |
| SCHEMBL4032608 | 0.74 | MMP1 (0.55) | CHRM5CHRM1SMN1; SMN2GAAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |