Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PKLR | P30613 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032099 | 0.92 | MAPK1 (0.55) | ALDH1A1HPGDL3MBTL1POLBGAA | |
| SCHEMBL1381658 | 0.88 | GAA (0.52) | ALDH1A1HPGDL3MBTL1POLBGAA | |
| SCHEMBL4034480 | 0.85 | GAA (0.57) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL4035095 | 0.82 | LMNA (0.60) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL4032374 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL4033651 | 0.80 | GAA (0.56) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL4038551 | 0.78 | MMP1 (0.45) | TP53 | |
| SCHEMBL4032584 | 0.76 | GAA (0.62) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL4036674 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HPGDPOLBGAAMAPK1 | |
| SCHEMBL1385884 | 0.74 | MAPK1 (0.59) | ALDH1A1HPGDPOLBGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | disclosed |