Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1842902 | 1.00 | MMP1 (0.46) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL4040784 | 1.00 | MMP1 (0.46) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL379356 | 0.87 | MMP1 (0.53) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL1841168 | 0.84 | L3MBTL1 (0.37) | MMP13KDM4EALDH1A1PIK3CAKMT2A | |
| SCHEMBL380092 | 0.81 | MMP2 (0.47) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL379268 | 0.81 | MMP2 (0.47) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL379926 | 0.81 | MMP2 (0.47) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL379484 | 0.81 | MMP2 (0.47) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL379148 | 0.81 | MMP2 (0.47) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL1842010 | 0.80 | MMP2 (0.47) | MMP2MMP3MMP9MMP13PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074093-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008023336-A2 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-02-28 | — | — | WO | disclosed |