Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 18/20 | 0.50 |
| ▸ | MMP3 | P08254 | 17/20 | 0.50 |
| ▸ | MMP9 | P14780 | 16/20 | 0.50 |
| ▸ | MMP7 | P09237 | 15/20 | 0.50 |
| ▸ | MMP13 | P45452 | 13/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033832 | 0.94 | MMP1 (0.49) | MMP1MMP3MMP9MMP7MMP13 | |
| SCHEMBL4035407 | 0.91 | MMP1 (0.51) | MMP1MMP3MMP9MMP7MMP13 | |
| SCHEMBL4036850 | 0.86 | ALDH1A1 (0.52) | MMP1MMP3MMP9MMP7MMP13 | |
| SCHEMBL4038132 | 0.84 | MMP1 (0.44) | MMP1MMP3MMP9MMP7MMP13 | |
| SCHEMBL4035648 | 0.84 | MMP1 (0.47) | MMP1MMP3MMP9MMP7MMP13 | |
| SCHEMBL4039378 | 0.83 | MMP1 (0.52) | MMP1MMP3MMP9MMP7MMP13 | |
| SCHEMBL4032675 | 0.82 | GAA (0.48) | MMP1MMP3MMP9MMP7MMP13 | |
| SCHEMBL4035075 | 0.82 | CHRM1 (0.40) | MMP1MMP3MMP9MMP7MMP13 | |
| SCHEMBL4032560 | 0.81 | MMP1 (0.43) | MMP1MMP3MMP9MMP7MMP13 | |
| SCHEMBL4032496 | 0.80 | ALDH1A1 (0.51) | MMP1MMP3MMP9MMP7MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |