Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 17/20 | 0.49 |
| ▸ | MMP3 | P08254 | 16/20 | 0.49 |
| ▸ | MMP9 | P14780 | 15/20 | 0.49 |
| ▸ | MMP13 | P45452 | 15/20 | 0.49 |
| ▸ | MMP7 | P09237 | 14/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036852 | 0.94 | MMP1 (0.50) | MMP1MMP3MMP9MMP13MMP7 | |
| SCHEMBL4035407 | 0.90 | MMP1 (0.51) | MMP1MMP3MMP9MMP13MMP7 | |
| SCHEMBL4039378 | 0.89 | MMP1 (0.52) | MMP1MMP3MMP9MMP13MMP7 | |
| SCHEMBL4032496 | 0.86 | ALDH1A1 (0.51) | MMP1MMP3MMP9MMP13MMP7 | |
| SCHEMBL4042256 | 0.85 | POLB (0.46) | MMP1MMP3MMP9MMP13MMP7 | |
| SCHEMBL4036877 | 0.84 | ALDH1A1 (0.52) | — | |
| SCHEMBL4033586 | 0.83 | ALDH1A1 (0.55) | — | |
| SCHEMBL4035716 | 0.82 | ALDH1A1 (0.46) | MMP1MMP3MMP9MMP13MMP7 | |
| SCHEMBL4038132 | 0.82 | MMP1 (0.44) | MMP1MMP3MMP9MMP13MMP7 | |
| SCHEMBL4035740 | 0.81 | ALDH1A1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |