Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | FABP1 | P07148 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036441 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL4034926 | 0.86 | SMN1; SMN2 (0.50) | ALDH1A1MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL1384751 | 0.86 | SMN1; SMN2 (0.50) | ALDH1A1MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL4038572 | 0.83 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2TP53TSHRGFER | |
| SCHEMBL4034764 | 0.80 | TSHR (0.61) | ALDH1A1KMT2ASMN1; SMN2TP53TSHR | |
| SCHEMBL4035097 | 0.79 | ALOX15 (0.47) | ALDH1A1KMT2ASMN1; SMN2ALOX15TSHR | |
| SCHEMBL4033204 | 0.79 | GAA (0.50) | ALDH1A1KMT2ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL1381140 | 0.79 | GAA (0.50) | ALDH1A1KMT2ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL1382163 | 0.79 | GAA (0.50) | ALDH1A1KMT2ASMN1; SMN2TP53ALOX15 | |
| Hydrochloric Acid SCHEMBL4036663 | 0.79 | ALOX15 (0.46) | ALDH1A1KMT2ASMN1; SMN2ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |