Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4036663 | 0.99 | ALOX15 (0.46) | ALOX15ALDH1A1GAAMAPK1TSHR | |
| SCHEMBL1380179 | 0.88 | GAA (0.51) | ALOX15ALDH1A1GAAMAPK1TSHR | |
| SCHEMBL13886846 | 0.88 | GAA (0.51) | ALOX15ALDH1A1GAAMAPK1TSHR | |
| Hydrochloric Acid SCHEMBL4035609 | 0.87 | GAA (0.50) | ALOX15ALDH1A1GAAMAPK1TSHR | |
| Hydrochloric Acid SCHEMBL4034494 | 0.87 | GAA (0.50) | ALOX15ALDH1A1GAAMAPK1TSHR | |
| SCHEMBL4038034 | 0.80 | MMP1 (0.53) | ALDH1A1 | |
| SCHEMBL4037035 | 0.79 | ALDH1A1 (0.48) | ALOX15ALDH1A1GAAMAPK1TSHR | |
| SCHEMBL4036441 | 0.79 | ALDH1A1 (0.48) | ALOX15ALDH1A1GAAMAPK1TSHR | |
| SCHEMBL14499802 | 0.78 | ALDH1A1 (0.51) | ALDH1A1GAATSHRGFERMAPT | |
| SCHEMBL4037270 | 0.78 | ALDH1A1 (0.51) | ALDH1A1GAATSHRGFERMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |