Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.42 |
| ▸ | PGR | P06401 | 3/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | DDO | Q99489 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655671 | 0.82 | LOXL2 (0.40) | NR3C1NR3C2PGR | |
| SCHEMBL4037362 | 0.75 | NR3C1 (0.57) | NR3C1NR3C2PGRDAODDO | |
| SCHEMBL6668593 | 0.74 | NR3C1 (0.43) | NR3C1NR3C2PGRARHRH4 | |
| SCHEMBL3707342 | 0.74 | NR3C1 (0.45) | NR3C1NR3C2PGRDAO | |
| SCHEMBL3714468 | 0.74 | NR3C1 (0.50) | NR3C1NR3C2PGR | |
| SCHEMBL5781026 | 0.72 | NR3C1 (0.49) | NR3C1 | |
| SCHEMBL4044986 | 0.70 | NR3C1 (0.45) | NR3C1NR3C2PGR | |
| SCHEMBL5821510 | 0.70 | LOXL2 (0.43) | NR3C1NR3C2PGR | |
| SCHEMBL5801773 | 0.70 | NR3C1 (0.37) | NR3C1NR3C2PGR | |
| SCHEMBL4223561 | 0.69 | NR3C1 (0.35) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051710-A2 | COMPOSITIONS AND METHODS FOR TREATING, REDUCING, AMELIORATING, OR ALLEVIATING POSTERIOR-SEGMENT OPHTHALMIC DISEASES | Bausch & Lomb Incorporated (US) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008021729-A2 | COMPOSITIONS AND METHODS FOR TREATING, REDUCING, AMELIORATING, OR ALLEVIATING POSTERIOR-SEGMENT OPHTHALMIC DISEASES | BAUSCH & LOMB INCORPORATED (US) | 2008-02-21 | — | — | WO | disclosed |