Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | PSIP1 | O75475 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036680 | 0.82 | MKNK1 (0.51) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4039532 | 0.82 | POLB (0.48) | PSIP1 | |
| SCHEMBL4040783 | 0.81 | MAP4K4 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7800828 | 0.78 | SMN1; SMN2 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9268728 | 0.77 | RARB (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4269790 | 0.76 | POLB (0.51) | PSIP1 | |
| SCHEMBL4213889 | 0.75 | MKNK1 (0.44) | — | |
| SCHEMBL296499 | 0.75 | GAA (0.41) | PTGS2AKR1C3AKR1C2CYP1A2CYP3A4 | |
| SCHEMBL7798369 | 0.75 | RARB (0.54) | — | |
| SCHEMBL9265764 | 0.74 | RARB (0.63) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074093-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-07-01 | — | — | EP | claimed |
| WO-2008023336-A2 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-02-28 | — | — | WO | claimed |