Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 9/20 | 0.42 |
| ▸ | ACACA | Q13085 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16751961 | 0.89 | KMT2A (0.43) | MKNK1MKNK2LMNAOXTR | |
| SCHEMBL4039535 | 0.89 | MKNK1 (0.42) | MKNK1MKNK2CTSANPC1LMNA | |
| SCHEMBL4040783 | 0.85 | MAP4K4 (0.44) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4037632 | 0.82 | IDO1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4039532 | 0.75 | POLB (0.48) | — | |
| SCHEMBL11117318 | 0.75 | AKR1C3 (0.56) | LMNA | |
| SCHEMBL7800828 | 0.74 | SMN1; SMN2 (0.43) | ACACBACACANPC1PSEN1PSEN2 | |
| SCHEMBL16751891 | 0.74 | AKR1C3 (0.43) | CTSAACACBPSEN1PSEN2APH1B | |
| SCHEMBL9268728 | 0.74 | RARB (0.50) | ACACBACACANPC1PSEN1PSEN2 | |
| SCHEMBL7014236 | 0.73 | NNMT (0.47) | MKNK1MKNK2ACACBNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074093-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-07-01 | — | — | EP | claimed |
| WO-2008023336-A2 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-02-28 | — | — | WO | claimed |