Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 6/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036680 | 0.85 | MKNK1 (0.51) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4037632 | 0.81 | IDO1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL13093763 | 0.79 | FTO (0.41) | MAP4K4FTOGCGRCD274 | |
| SCHEMBL7800828 | 0.78 | SMN1; SMN2 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4039535 | 0.77 | MKNK1 (0.42) | SLC22A12LMNA | |
| SCHEMBL4039532 | 0.76 | POLB (0.48) | — | |
| SCHEMBL11117318 | 0.76 | AKR1C3 (0.56) | AKR1C3AKR1C2AKR1C1PTGS1PTGS2 | |
| SCHEMBL16751961 | 0.76 | KMT2A (0.43) | AKR1C3AKR1C2AKR1C1PTGS1LMNA | |
| SCHEMBL7798369 | 0.75 | RARB (0.54) | LMNA | |
| SCHEMBL9268728 | 0.75 | RARB (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074093-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-07-01 | — | — | EP | claimed |
| WO-2008023336-A2 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-02-28 | — | — | WO | claimed |