Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PSIP1 | O75475 | 5/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4269790 | 0.95 | POLB (0.51) | POLBPSIP1SMN1; SMN2 | |
| SCHEMBL10896682 | 0.84 | POLB (0.49) | POLBSMN1; SMN2 | |
| SCHEMBL4037632 | 0.82 | IDO1 (0.43) | PSIP1 | |
| SCHEMBL9938570 | 0.81 | LMNA (0.49) | POLBFFAR1SMN1; SMN2 | |
| SCHEMBL11762062 | 0.81 | MMP13 (0.46) | — | |
| SCHEMBL4038598 | 0.81 | PSEN1 (0.61) | FFAR1 | |
| SCHEMBL633268 | 0.80 | ESR1 (0.49) | — | |
| SCHEMBL643461 | 0.80 | CYP2C19 (0.53) | POLBSMN1; SMN2 | |
| SCHEMBL19228532 | 0.80 | CYP2C19 (0.53) | POLBSMN1; SMN2 | |
| SCHEMBL510548 | 0.80 | ALDH1A1 (0.56) | POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074093-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-07-01 | — | — | EP | claimed |
| WO-2008023336-A2 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-02-28 | — | — | WO | claimed |