Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4037178 | 0.86 | GCGR (0.77) | GCGRALDH1A1HTTHSD17B10KDM4E | |
| SCHEMBL4039316 | 0.85 | GCGR (0.59) | GCGRALDH1A1HTTHSD17B10KDM4E | |
| SCHEMBL4040353 | 0.81 | GCGR (0.82) | GCGRALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL4035540 | 0.79 | GCGR (0.77) | GCGRALDH1A1HSD17B10KDM4EMAPT | |
| SCHEMBL4038178 | 0.77 | GCGR (0.46) | GCGRALDH1A1HTTHSD17B10KDM4E | |
| SCHEMBL4037335 | 0.77 | GCGR (0.72) | GCGRALDH1A1HTTHSD17B10KDM4E | |
| SCHEMBL2648406 | 0.76 | GCGR (0.70) | GCGRALDH1A1HTTHSD17B10KDM4E | |
| SCHEMBL4037054 | 0.76 | GCGR (0.72) | GCGRALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL4046144 | 0.75 | GCGR (0.59) | GCGRALDH1A1HTTHSD17B10KDM4E | |
| SCHEMBL6316704 | 0.74 | GCGR (0.71) | GCGRALDH1A1HTTHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 963 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549655-B1 | SUBSTITUTED BICYCLIC THIOPHENE DERIVATIVES, COMPOSTIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO INC (US) | 2009-01-21 | — | — | EP | claimed |
| EP-1549655-A4 | SUBSTITUTED BICYCLIC THIOPHENE DERIVATIVES, COMPOSTIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO INC (US) | 2006-05-31 | — | — | EP | claimed |
| US-20050239865-A1 | Substituted bicyclic thiophene derivatives, compositions containing such compounds and methods of use | MERCK SHARP & DOHME CORP. | 2005-10-27 | — | — | US | claimed |
| EP-1549655-A2 | SUBSTITUTED BICYCLIC THIOPHENE DERIVATIVES, COMPOSTIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | Merck & Co., Inc. (US) | 2005-07-06 | — | — | EP | claimed |
| WO-2004024065-A2 | SUBSTITUTED BICYCLIC THIOPHENE DERIVATIVES, COMPOSTIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 2004-03-25 | — | — | WO | claimed |
| US-12048207-B2 | Display device and method for manufacturing the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2024-07-23 | — | — | US | disclosed |
| US-20240237435-A1 | Semiconductor Device, Display Apparatus, and Electronic Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2024-07-11 | — | — | US | disclosed |
| US-12034080-B2 | Semiconductor device, method for manufacturing the same, or display device including the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2024-07-09 | — | — | US | disclosed |
| US-20240213356-A1 | METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2024-06-27 | — | — | US | disclosed |
| US-12002876-B2 | Semiconductor device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2024-06-04 | — | — | US | disclosed |
| US-20240173014-A1 | ELECTRONIC DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2024-05-30 | — | — | US | disclosed |
| US-20240179987-A1 | Display Apparatus, Electronic Device, and Method of Manufacturing Semiconductor Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2024-05-30 | — | — | US | disclosed |
| US-7476420-B2 | Process for producing metal oxide films at low temperatures | ASM INTERNATIONAL N.V. (NL) | 2009-01-13 | — | — | US | disclosed |
| US-20080318423-A9 | PROCESS FOR PRODUCING METAL OXIDE FILMS AT LOW TEMPERATURES | SKARP JARMO | 2008-12-25 | — | — | US | disclosed |
| US-7273876-B2 | Substituted bicylic thiophene derivatives, compositions containing such compounds and methods of use | MERCK & CO., INC. (US) | 2007-09-25 | — | — | US | disclosed |
| EP-1549655-A4 | SUBSTITUTED BICYCLIC THIOPHENE DERIVATIVES, COMPOSTIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO INC (US) | 2006-05-31 | — | — | EP | disclosed |
| US-20050239865-A1 | Substituted bicyclic thiophene derivatives, compositions containing such compounds and methods of use | MERCK SHARP & DOHME CORP. | 2005-10-27 | — | — | US | disclosed |
| EP-1549655-A2 | SUBSTITUTED BICYCLIC THIOPHENE DERIVATIVES, COMPOSTIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | Merck & Co., Inc. (US) | 2005-07-06 | — | — | EP | disclosed |
| US-20050112874-A1 | Process for producing metal oxide films at low temperatures | ASM INTERNATIONAL N.V. (NL) | 2005-05-26 | — | — | US | disclosed |
| WO-2004024065-A2 | SUBSTITUTED BICYCLIC THIOPHENE DERIVATIVES, COMPOSTIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 2004-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239865-A1 | Substituted bicyclic thiophene derivatives, compositions containing such compounds and methods of use | GLP1R, GCGR, GPR119 | GCGR 2/4885ALDH1A1 4206/4885HTT 2047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.