Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 12/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033843 | 0.84 | PRKDC (0.47) | ERN1PRKDCALDH1A1KDM4ETSHR | |
| SCHEMBL11763981 | 0.84 | ERN1 (0.46) | ERN1PRKDCALDH1A1KDM4ETSHR | |
| SCHEMBL18529824 | 0.81 | ERN1 (0.48) | ERN1PRKDCEGFRERBB2ALDH1A1 | |
| SCHEMBL14427622 | 0.79 | ERN1 (0.58) | ERN1PRKDCALDH1A1KDM4ETSHR | |
| SCHEMBL2743529 | 0.78 | ALDH1A1 (0.57) | ERN1PRKDCALDH1A1KDM4ETSHR | |
| SCHEMBL15225994 | 0.78 | PDGFRB (0.41) | ERN1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL4038581 | 0.74 | ALDH1A1 (0.47) | ERN1ALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL15226073 | 0.72 | ALDH1A1 (0.48) | ERN1ALDH1A1 | |
| SCHEMBL2743635 | 0.72 | PRKDC (0.58) | ERN1PRKDCEGFRALDH1A1KDM4E | |
| SCHEMBL29191184 | 0.71 | CA1 (0.41) | ERN1EGFRERBB2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066632-B1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARM CORP (KR) | 2013-09-04 | — | — | EP | disclosed |
| EP-2066632-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | Chong Kun Dang Pharmaceutical Corp. (KR) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008038955-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-04-03 | — | — | WO | disclosed |