Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PRKDC | P78527 | 2/20 | 0.52 |
| ▸ | ERN1 | O75460 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14427622 | 0.89 | ERN1 (0.58) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL3751505 | 0.85 | ALDH1A1 (0.59) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL11763981 | 0.84 | ERN1 (0.46) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL28734008 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL4033843 | 0.82 | PRKDC (0.47) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL28458355 | 0.82 | ERN1 (0.52) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL20123251 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL38661111 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL10400558 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL7004928 | 0.80 | ERN1 (0.67) | ALDH1A1KDM4ETSHRTDP1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178578-B2 | Chemical compounds | THE UNIVERSITY OF MANCHESTER (GB) | 2012-05-15 | — | — | US | disclosed |
| US-20100041881-A1 | OPTICALLY ACTIVE AMMONIUM SALT COMPOUND, PRODUCTION INTERMEDIATE THEREOF, AND PRODUCTION METHOD THEREOF | NIPPON SODA CO., LTD. (JP) | 2010-02-18 | — | — | US | disclosed |
| US-20100016261-A1 | CHEMICAL COMPOUNDS | THE UNIVERSITY OF MANCHESTER (GB) | 2010-01-21 | — | — | US | disclosed |
| EP-2101755-A2 | POLYALKYLOXYDIBENZ (C,E) OXEPINE DERIVATIVES AS MEDICAMENTS | The University of Manchester (GB) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008075048-A2 | POLYALKYLOXYDIBENZ ( C, E) OXEPINE DERIVATIVES AS MEDICAMENTS | THE UNIVERSITY OF MANCHESTER (GB) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016261-A1 | CHEMICAL COMPOUNDS | CYP11B2, MPO, PIGO | ALDH1A1 13/4885KDM4E 3104/4885TSHR 3927/4885 |
| US-20100041881-A1 | OPTICALLY ACTIVE AMMONIUM SALT COMPOUND, PRODUCTION INTERMEDIATE THEREOF, AND PRODUCTION METHOD THEREOF | ASS1, ACSL3, AGT | ALDH1A1 1740/4885KDM4E 4278/4885TSHR 1060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.