SCHEMBL4038906

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2829838	0.89	LMNA (0.59)	LMNAMAPTDRD2DRD4TP53
	SCHEMBL2827619	0.86	LMNA (0.59)	LMNAMAPTDRD2DRD4TP53
	SCHEMBL4043208	0.83	LMNA (0.70)	LMNADRD2DRD4KDM4ECA12
	SCHEMBL4041075	0.83	LMNA (0.71)	LMNACA12CA9SRD5A2SRD5A1
	Hydrochloric Acid SCHEMBL4045240	0.82	LMNA (0.68)	LMNADRD2DRD4KDM4ECA12
	SCHEMBL7770745	0.80	LMNA (0.46)	LMNAMAPTDRD2DRD4TP53
	SCHEMBL962986	0.76	MAPT (0.50)	LMNAMAPTDRD2DRD4TP53
	SCHEMBL7769552	0.75	MAPT (0.43)	LMNAMAPTDRD2DRD4TP53
	SCHEMBL4038858	0.73	LMNA (0.54)	LMNAMAPTDRD2DRD4TP53
	SCHEMBL9949074	0.73	CA12 (0.54)	LMNAMAPTDRD2DRD4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.