Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 1.00 |
| ▸ | CTSS | P25774 | 3/20 | 0.75 |
| ▸ | CCR1 | P32246 | 2/20 | 0.47 |
| ▸ | CTSV | O60911 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5941421 | 1.00 | CTSK (1.00) | CTSKCTSSCCR1CTSVCTSL | |
| SCHEMBL4210233 | 1.00 | CTSK (1.00) | CTSKCTSSCCR1CTSVCTSL | |
| SCHEMBL4210236 | 1.00 | CTSK (1.00) | CTSKCTSSCCR1CTSVCTSL | |
| SCHEMBL5942073 | 0.94 | CTSK (0.88) | CTSKCTSSCCR1CTSVCTSL | |
| SCHEMBL5942080 | 0.94 | CTSK (0.88) | CTSKCTSSCCR1CTSVCTSL | |
| SCHEMBL4041855 | 0.91 | CTSK (0.84) | CTSKCTSSCCR1MEN1KMT2A | |
| SCHEMBL4219542 | 0.91 | CTSK (0.84) | CTSKCTSSCCR1MEN1KMT2A | |
| SCHEMBL4219546 | 0.91 | CTSK (0.84) | CTSKCTSSCCR1MEN1KMT2A | |
| SCHEMBL5942295 | 0.91 | CTSK (0.84) | CTSKCTSSCCR1MEN1KMT2A | |
| SCHEMBL4369360 | 0.91 | CTSK (0.84) | CTSKCTSSCCR1CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |
| US-20060100431-A1 | Biologically active compounds | AMURA THERAPEUTICS LIMITED (GB) | 2006-05-11 | — | — | US | claimed |
| EP-2185563-B1 | OXASPIROCYCLIC SPIRO-SUBSTITUTED TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| EP-1537123-B1 | AMINO-SUBSTITUTED CYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | GLAXO GROUP LTD (GB) | 2009-04-29 | — | — | EP | disclosed |
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |
| EP-2020413-A1 | Oxaspirocyclical spiro-substituted tetram and tetron acid derivatives | Bayer CropScience AG (DE) | 2009-02-04 | — | — | EP | disclosed |
| US-20060100431-A1 | Biologically active compounds | AMURA THERAPEUTICS LIMITED (GB) | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100431-A1 | Biologically active compounds | SOST, CTSK, CTSS | CTSK 2/4885CTSS 3/4885CCR1 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.