Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.56 |
| ▸ | HPGDS | O60760 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.39 |
| ▸ | HTR3B | O95264 | 4/20 | 0.39 |
| ▸ | HTR3A | P46098 | 4/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041554 | 0.95 | CTSK (0.55) | CTSKHPGDSCTSSCTSBCHRNA7 | |
| SCHEMBL4039928 | 0.94 | CTSK (0.54) | CTSKHPGDSCTSSCTSBCHRNA7 | |
| SCHEMBL4043610 | 0.94 | CTSK (0.53) | CTSKHPGDSCTSSCTSBCHRNA7 | |
| SCHEMBL4046731 | 0.93 | CTSK (0.56) | CTSKHPGDSCTSSCTSBCHRNA7 | |
| SCHEMBL4045241 | 0.93 | CTSK (0.55) | CTSKHPGDSCTSSCTSBCHRNA7 | |
| SCHEMBL4042777 | 0.92 | CTSK (0.57) | CTSKHPGDSCTSSCTSBCHRNA7 | |
| SCHEMBL4040231 | 0.92 | CTSK (0.56) | CTSKHPGDSCTSSCTSBCHRNA7 | |
| SCHEMBL4042686 | 0.91 | CTSK (0.58) | CTSKHPGDSCTSSCTSBCHRNA7 | |
| SCHEMBL4043010 | 0.91 | CTSK (0.55) | CTSKHPGDSCTSSCTSBCHRNA7 | |
| SCHEMBL4045405 | 0.90 | CTSK (0.53) | CTSKHPGDSCTSSCTSBCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343807-B1 | DIARYL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITS C VIRUS | SCHERING CORP (US) | 2009-04-29 | — | — | EP | claimed |
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |
| EP-1322309-B1 | HIGH AFFINITY SMALL MOLECULE C5A RECEPTOR MODULATORS | NEUROGEN CORP (US) | 2008-08-13 | — | — | EP | claimed |
| EP-1341769-B1 | BACTERIAL GYRASE INHIBITORS AND USES THEREOF | VERTEX PHARMA (US) | 2007-10-17 | — | — | EP | claimed |
| US-20060100431-A1 | Biologically active compounds | AMURA THERAPEUTICS LIMITED (GB) | 2006-05-11 | — | — | US | claimed |
| EP-0161769-B1 | ENKEPHALINASE INHIBITORS | E.R. Squibb & Sons, Inc. (US) | 1987-10-28 | — | — | EP | claimed |
| EP-2540164-A1 | Active agent combinations with insecticide properties | Bayer CropScience AG (DE) | 2013-01-02 | — | — | EP | disclosed |
| EP-1686859-B1 | COMBINATION OF ACTIVE SUBSTANCES WITH INSECTICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2012-08-01 | — | — | EP | disclosed |
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |
| EP-1982594-A1 | Active agent combinations with insecticidal and acaricidal properties | Bayer CropScience AG (DE) | 2008-10-22 | — | — | EP | disclosed |
| EP-1974607-A2 | Selective insecticides based on anthranilic acid diamides and safeners | Bayer CropScience AG (DE) | 2008-10-01 | — | — | EP | disclosed |
| US-20060100431-A1 | Biologically active compounds | AMURA THERAPEUTICS LIMITED (GB) | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100431-A1 | Biologically active compounds | SOST, CTSK, CTSS | CTSK 2/4885HPGDS 603/4885CTSS 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.