Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 3/20 | 0.48 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 5/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3966077 | 0.85 | GBA1 (0.56) | GBA1SLC6A4HTR2CCYP2D6SLC6A2 | |
| SCHEMBL4047455 | 0.83 | MEN1 (0.37) | GBA1SLC6A4HTR2CHTR7CYP1A2 | |
| SCHEMBL11606103 | 0.79 | GBA1 (0.50) | GBA1SLC6A4HTR2CCYP1A2HTR2A | |
| SCHEMBL3969439 | 0.79 | HTR2C (0.53) | GBA1SLC6A4HTR2CCYP2D6SLC6A2 | |
| SCHEMBL28022009 | 0.79 | GBA1 (0.58) | GBA1SLC6A4CYP2D6SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL18280078 | 0.78 | GBA1 (0.56) | GBA1SLC6A4CYP2D6SLC6A2SLC6A3 | |
| SCHEMBL29889399 | 0.76 | SLC6A4 (0.48) | GBA1SLC6A4HTR2CCYP2D6SLC6A2 | |
| SCHEMBL28818269 | 0.76 | SLC6A4 (0.48) | GBA1SLC6A4HTR2CCYP2D6SLC6A2 | |
| SCHEMBL10559094 | 0.74 | SLC6A4 (0.49) | GBA1SLC6A4HTR2CHTR7SLC6A2 | |
| SCHEMBL11610662 | 0.74 | TDP1 (0.51) | GBA1SLC6A4HTR7MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1279519-B1 | Image forming material and ammonium compound | FUJIFILM CORP (JP) | 2009-07-01 | — | — | EP | disclosed |
| US-6958205-B2 | Usable as offset printing master; positive image forming material useful as positive planographic printing plate precursor for infrared laser which planographic printing plate precursor is used for direct plate-making from digital signal | FUJI PHOTO FILM CO., LTD. (JP) | 2005-10-25 | — | — | US | disclosed |
| US-20030143481-A1 | Usable as offset printing master; positive image forming material useful as positive planographic printing plate precursor for infrared laser which planographic printing plate precursor is used for direct plate-making from digital signal | FUJI PHOTO FILM CO., LTD. | 2003-07-31 | — | — | US | disclosed |
| EP-1279519-A2 | Image forming material and ammonium compound | FUJI PHOTO FILM CO., LTD. (JP) | 2003-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030143481-A1 | Usable as offset printing master; positive image forming material useful as positive planographic printing plate precursor for infrared laser which planographic printing plate precursor is used for direct plate-making from digital signal | COL1A1, ROCK1, P4HA1 | SLC6A4 4299/4885SLC6A2 4375/4885SLC6A3 3942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.