Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4039561 | 0.83 | GBA1 (0.49) | MEN1KMT2ASLC6A4GBA1CHRM1 | |
| SCHEMBL3966077 | 0.72 | GBA1 (0.56) | SLC6A4GBA1LMNACYP2D6HTR2C | |
| Aziridine SCHEMBL5185484 | 0.72 | ALDH1A1 (0.50) | HTTKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7372408 | 0.72 | NMT1 (0.42) | MEN1KMT2AHTR6CHRM1HTT | |
| SCHEMBL2942079 | 0.71 | CYP2D6 (0.43) | MEN1KMT2ASLC6A4HTR6HTT | |
| Piperazine SCHEMBL5875357 | 0.71 | ALDH1A1 (0.49) | HTTKDM4EALDH1A1LMNAMAPT | |
| Piperazine SCHEMBL7635861 | 0.71 | ALDH1A1 (0.49) | HTTKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL3582891 | 0.70 | CYP2D6 (0.42) | MEN1KMT2AHTR6HTTKDM4E | |
| SCHEMBL3582264 | 0.70 | CYP2D6 (0.42) | MEN1KMT2AHTR6HTTKDM4E | |
| SCHEMBL23850965 | 0.69 | KDM4E (0.51) | MEN1KMT2ASLC6A4HTR6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1279519-B1 | Image forming material and ammonium compound | FUJIFILM CORP (JP) | 2009-07-01 | — | — | EP | disclosed |
| US-6958205-B2 | Usable as offset printing master; positive image forming material useful as positive planographic printing plate precursor for infrared laser which planographic printing plate precursor is used for direct plate-making from digital signal | FUJI PHOTO FILM CO., LTD. (JP) | 2005-10-25 | — | — | US | disclosed |
| US-20030143481-A1 | Usable as offset printing master; positive image forming material useful as positive planographic printing plate precursor for infrared laser which planographic printing plate precursor is used for direct plate-making from digital signal | FUJI PHOTO FILM CO., LTD. | 2003-07-31 | — | — | US | disclosed |
| EP-1279519-A2 | Image forming material and ammonium compound | FUJI PHOTO FILM CO., LTD. (JP) | 2003-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030143481-A1 | Usable as offset printing master; positive image forming material useful as positive planographic printing plate precursor for infrared laser which planographic printing plate precursor is used for direct plate-making from digital signal | COL1A1, ROCK1, P4HA1 | MEN1 1113/4885KMT2A 2332/4885SLC6A4 4299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.