SCHEMBL4040223

SCHEMBL4040223

O=C(Cc1ccccc1)Nc1ccccc1C(=O)O

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.82
L3MBTL1 Q9Y468 2/20 0.82
KDM4E B2RXH2 4/20 0.77
LMNA P02545 4/20 0.77
SMN1; SMN2 Q16637 2/20 0.77
KDM6B O15054 1/20 0.68
KDM4D Q6B0I6 1/20 0.68
KDM4C Q9H3R0 1/20 0.68
HPGD P15428 4/20 0.65
KMT2A Q03164 5/20 0.63
MEN1 O00255 2/20 0.61
PTGER4 P35408 1/20 0.61
CFD P00746 1/20 0.61
PKM P14618 1/20 0.59
EPHX2 P34913 1/20 0.59
GAA P10253 1/20 0.58
ATM Q13315 1/20 0.58
POLB P06746 1/20 0.58
MAPT P10636 1/20 0.58
CTSK P43235 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8437112 0.98 ALDH1A1 (0.79) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL5696443 0.94 ALDH1A1 (0.73) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL14855999 0.94 ALDH1A1 (0.73) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL12700260 0.90 ALDH1A1 (0.68) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL14825284 0.89 KMT2A (0.67) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL4629164 0.88 ALDH1A1 (0.75) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL3628197 0.88 SIRT2 (0.70) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL10651597 0.86 HPGD (0.66) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL9003567 0.86 ALDH1A1 (0.63) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL5696444 0.86 ALDH1A1 (0.68) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115942929-A Oil-in-water type emulsion composition 株式会社资生堂 2023-04-07 CN disclosed
CN-110536677-B Method for producing ultraviolet protective film 花王株式会社 2023-01-03 CN disclosed
CN-115461030-A Cleaning agent composition 株式会社资生堂 2022-12-09 CN disclosed
CN-115279332-A Composition containing lamellar gel, emulsified composition and external composition for skin 株式会社资生堂 2022-11-01 CN disclosed
CN-115151239-A Oil-in-water type emulsion composition 株式会社资生堂 2022-10-04 CN disclosed
CN-114502135-A W/O/W type emulsified composition 株式会社资生堂 2022-05-13 CN disclosed
CN-114466647-A Solid water-in-oil type emulsion cosmetic 株式会社资生堂 2022-05-10 CN disclosed
CN-113873996-A Personal care compositions and malodor suppression methods 株式会社资生堂 2021-12-31 CN disclosed
CN-113329794-A Skin external preparation and method for improving ultraviolet protection effect 株式会社资生堂 2021-08-31 CN disclosed
CN-113248399-A O-amino aromatic amide derivative and preparation method and application thereof 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2021-08-13 CN disclosed
EP-1663237-A4 FUSED RING HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS ICAGEN INC (US) 2009-04-29 EP disclosed
EP-1585522-A4 QUINAZOLINONES AS POTASSIUM CHANNEL MODULATORS ICAGEN INC (US) 2006-08-09 EP disclosed
EP-1663237-A2 FUSED RING HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS Icagen, Inc. (US) 2006-06-07 EP disclosed
EP-1585522-A2 QUINAZOLINONES AS POTASSIUM CHANNEL MODULATORS Icagen, Inc. (US) 2005-10-19 EP disclosed
WO-2005025293-A2 FUSED RING HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS ICAGEN, INC. (US) 2005-03-24 WO disclosed
WO-2004058704-A2 QUINAZOLINONES AS POTASSIUM CHANNEL MODULATORS ICAGEN, INC. (US) 2004-07-15 WO disclosed
WO-2003106435-A1 FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF SANKYO COMPANY, LIMITED (JP) 2003-12-24 WO disclosed
WO-2000066751-A1 EXPRESSION CASSETTE FOR EFFICIENT PRODUCTION OF A PROTEIN DSM N.V. (NL) 2000-11-09 WO disclosed
US-4554250-A Method of increased production of penicillin acylase and plasmid employed therein E. R. SQUIBB & SONS, INC. (US) 1985-11-19 US disclosed
US-4044196-A Crosslinked copolymers of α,β-olefinically unsaturated dicarboxylic anhydrides BAYER AKTIENGESELLSCHAFT (DT) 1977-08-23 US disclosed