SCHEMBL9003567

SCHEMBL9003567

[NH]C(=O)c1ccccc1NC(=O)Cc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.63
LMNA P02545 3/20 0.63
KDM4E B2RXH2 3/20 0.63
L3MBTL1 Q9Y468 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
HPGD P15428 3/20 0.61
EPHX2 P34913 1/20 0.56
KMT2A Q03164 5/20 0.55
GAA P10253 2/20 0.55
ATM Q13315 1/20 0.55
SIRT2 Q8IXJ6 1/20 0.53
PKM P14618 2/20 0.52
KDM6B O15054 1/20 0.52
KDM4D Q6B0I6 1/20 0.52
KDM4C Q9H3R0 1/20 0.52
KCNQ2 O43526 1/20 0.52
MAPK8 P45983 1/20 0.52
MAPK10 P53779 1/20 0.52
RXFP1 Q9HBX9 1/20 0.52
MEN1 O00255 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4040223 0.86 ALDH1A1 (0.82) ALDH1A1LMNAKDM4EL3MBTL1SMN1; SMN2
SCHEMBL3628197 0.85 SIRT2 (0.70) ALDH1A1LMNAKDM4EL3MBTL1SMN1; SMN2
SCHEMBL8437112 0.85 ALDH1A1 (0.79) ALDH1A1LMNAKDM4EL3MBTL1SMN1; SMN2
SCHEMBL10651597 0.83 HPGD (0.66) ALDH1A1LMNAKDM4EL3MBTL1SMN1; SMN2
Zinc Ion SCHEMBL8437110 0.82 ALDH1A1 (0.61) ALDH1A1LMNAKDM4EL3MBTL1SMN1; SMN2
SCHEMBL5696443 0.81 ALDH1A1 (0.73) ALDH1A1LMNAKDM4EL3MBTL1SMN1; SMN2
SCHEMBL13936057 0.81 KDM4E (0.74) ALDH1A1LMNAKDM4EL3MBTL1SMN1; SMN2
SCHEMBL31324947 0.81 KDM4E (0.74) ALDH1A1LMNAKDM4EL3MBTL1SMN1; SMN2
SCHEMBL28926541 0.81 HPGD (0.62) ALDH1A1LMNAKDM4EL3MBTL1SMN1; SMN2
SCHEMBL28609648 0.81 HPGD (0.62) ALDH1A1LMNAKDM4EL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0469954-B1 Process for preparing aqueous dispersion of copolymers RHONE POULENC CHIMIE (FR) 1996-09-25 EP disclosed
EP-0469954-A1 Process for preparing aqueous dispersion of copolymers RHONE-POULENC CHIMIE (FR) 1992-02-05 EP disclosed