SCHEMBL8437112

SCHEMBL8437112

O=C(Cc1ccccc1)Nc1ccccc1C(=O)O.[Zn]

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.79
L3MBTL1 Q9Y468 2/20 0.79
KDM4E B2RXH2 4/20 0.74
LMNA P02545 4/20 0.74
SMN1; SMN2 Q16637 2/20 0.74
KDM6B O15054 1/20 0.66
KDM4D Q6B0I6 1/20 0.66
KDM4C Q9H3R0 1/20 0.66
HPGD P15428 4/20 0.63
KMT2A Q03164 5/20 0.61
MEN1 O00255 2/20 0.60
PTGER4 P35408 1/20 0.60
CFD P00746 1/20 0.59
PKM P14618 1/20 0.58
EPHX2 P34913 1/20 0.58
GAA P10253 1/20 0.56
ATM Q13315 1/20 0.56
POLB P06746 1/20 0.56
MAPT P10636 1/20 0.56
CTSK P43235 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4040223 0.98 ALDH1A1 (0.82) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL14855999 0.92 ALDH1A1 (0.73) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL5696443 0.92 ALDH1A1 (0.73) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL12700260 0.89 ALDH1A1 (0.68) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL14825284 0.87 KMT2A (0.67) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL4629164 0.87 ALDH1A1 (0.75) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL3628197 0.86 SIRT2 (0.70) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL10651597 0.85 HPGD (0.66) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL9003567 0.85 ALDH1A1 (0.63) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2
SCHEMBL5696444 0.85 ALDH1A1 (0.68) ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0963858-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1999-12-15 EP disclosed
EP-0844099-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1998-05-27 EP disclosed