Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.56 |
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | CTSV | O60911 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043683 | 0.95 | CTSK (0.54) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4047026 | 0.95 | CTSK (0.60) | CTSKCTSSCTSL | |
| SCHEMBL4050121 | 0.94 | CTSK (0.54) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4046427 | 0.91 | CTSK (0.58) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4046824 | 0.90 | CTSK (0.70) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4044579 | 0.89 | CTSK (0.71) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4042313 | 0.89 | CTSK (0.64) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4041651 | 0.88 | CTSK (0.55) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4045496 | 0.88 | CTSK (0.60) | CTSKCTSSCTSVCTSLCCR1 | |
| SCHEMBL4048280 | 0.88 | CTSK (0.56) | CTSKCTSSCTSVCTSLCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514417-B2 | A1 adenosine receptor agonists | CV THERAPEUTICS, INC. (US) | 2009-04-07 | — | — | US | disclosed |