Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046022 | 0.83 | NOS1 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL4040692 | 0.79 | LCK (0.31) | — | |
| SCHEMBL4042248 | 0.76 | PRMT5 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL6644634 | 0.74 | TLR8 (0.31) | — | |
| SCHEMBL6646169 | 0.67 | LCK (0.31) | — | |
| SCHEMBL6644633 | 0.67 | IKBKB (0.37) | — | |
| SCHEMBL4043255 | 0.67 | NOS1 (0.40) | NOS3NOS1NOS2 | |
| SCHEMBL4038533 | 0.65 | LCK (0.61) | — | |
| SCHEMBL4040159 | 0.64 | LCK (0.38) | NOS1NOS2 | |
| SCHEMBL6645234 | 0.64 | HRH4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066286-B1 | HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2009-04-29 | — | — | EP | claimed |