Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4040696 | 0.79 | NOS3 (0.32) | — | |
| SCHEMBL4042246 | 0.76 | LCK (0.35) | LCK | |
| SCHEMBL6644634 | 0.68 | TLR8 (0.31) | — | |
| SCHEMBL4036269 | 0.67 | LCK (0.55) | LCK | |
| SCHEMBL4036362 | 0.65 | LCK (0.41) | LCK | |
| SCHEMBL6645541 | 0.64 | PDE10A (0.49) | LCK | |
| SCHEMBL31040798 | 0.62 | LCK (0.37) | LCK | |
| SCHEMBL6646169 | 0.62 | LCK (0.31) | LCK | |
| SCHEMBL31060458 | 0.61 | LCK (0.40) | LCK | |
| SCHEMBL28814208 | 0.61 | DHFR (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066286-B1 | HETEROCYCLO-SUBSTITUTED IMIDAZOPYRAZINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2009-04-29 | — | — | EP | claimed |