SCHEMBL4040993

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4042637	0.91	CTSK (0.43)	CTSKKDM4EHSD17B10CTSLCTSS
	SCHEMBL4041880	0.90	CTSK (0.42)	CTSKCTSLCTSSL3MBTL1DPP4
	SCHEMBL4040009	0.89	CTSK (0.42)	CTSKKDM4ECYP2C9CYP2C19LMNA
	SCHEMBL4043803	0.89	CTSK (0.42)	CTSKKDM4EHSD17B10CTSLCTSS
	SCHEMBL4043087	0.87	KDM4E (0.39)	CTSKKDM4ECYP2C9CYP2C19HSD17B10
	SCHEMBL4041553	0.86	CTSK (0.41)	CTSKCTSLCTSSL3MBTL1DPP4
	SCHEMBL4043889	0.84	KDM4E (0.41)	CTSKKDM4ECYP2C9CYP2C19HSD17B10
	SCHEMBL4042730	0.84	CTSK (0.40)	CTSKCTSLCTSSL3MBTL1DPP4
	SCHEMBL4043258	0.82	KDM4E (0.39)	CTSKKDM4ECYP2C9CYP2C19HSD17B10
	SCHEMBL4043201	0.82	KDM4E (0.40)	CTSKKDM4ECYP2C9CYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.