SCHEMBL4042889

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4040155	0.89	GRIA1 (0.42)	CD274PDCD1GRIA1GRIA3PDE4D
	SCHEMBL3959509	0.87	GRIA1 (0.34)	GRIA1GRIA3PDE4DMEN1ALDH1A1
	SCHEMBL4038841	0.85	DRD2 (0.42)	CD274PDCD1FFAR1
	SCHEMBL4042014	0.85	GRIA1 (0.34)	GRIA1GRIA3PDE4DGRM5FFAR1
	SCHEMBL4041256	0.84	GRIA1 (0.42)	CD274PDCD1GRIA1GRIA3PDE4D
	SCHEMBL4044781	0.84	CYP11B2 (0.39)	GRIA1GRIA3PDE4DMEN1ALDH1A1
	SCHEMBL4050316	0.83	PDCD1 (0.55)	CD274PDCD1NPC1ALDH1A1RAB9A
	SCHEMBL4041349	0.83	GRIA1 (0.38)	GRIA1GRIA3PDE4DALDH1A1GRM5
	SCHEMBL4044723	0.83	GRIA1 (0.34)	GRIA1GRIA3PDE4DALDH1A1GRM5
	SCHEMBL4042421	0.83	CD274 (0.40)	CD274PDCD1MEN1NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.