⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10718790 | 0.83 | — | — | |
| SCHEMBL11819708 | 0.72 | KDM4E (0.32) | — | |
| SCHEMBL4762135 | 0.58 | NOS3 (0.31) | — | |
| SCHEMBL11817339 | 0.58 | KDM4E (0.30) | — | |
| SCHEMBL678723 | 0.56 | — | — | |
| SCHEMBL1515575 | 0.53 | — | — | |
| SCHEMBL1005181 | 0.53 | — | — | |
| SCHEMBL12834817 | 0.47 | — | — | |
| SCHEMBL24444525 | 0.44 | — | — | |
| SCHEMBL23743116 | 0.44 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638938-B1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF ORTHOPOXVIRUS INFECTIONS AND ASSOCIATED DISEASES | SIGA TECH INC (US) | 2017-04-12 | — | — | EP | disclosed |
| EP-3006425-A1 | PHARMACEUTICAL COMPOSITION FOR USE IN THE TREATMENT AND PREVENTION OF ORTHOPOXVIRUS INFECTIONS AND ASSOCIATED DISEASES | Siga Technologies, Inc. (US) | 2016-04-13 | — | — | EP | disclosed |
| US-9045418-B2 | Compounds, compositions and methods for treatment and prevention of Orthopoxvirus infections and associated diseases | SIGA TECHNOLOGIES, INC. (US) | 2015-06-02 | — | — | US | disclosed |
| US-20140316145-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF ORTHOPOXVIRUS INFECTIONS AND ASSOCIATED DISEASES | SIGA TECHNOLOGIES, INC., (US) | 2014-10-23 | — | — | US | disclosed |
| US-20140301979-A1 | ANTI-ARENAVIRAL COMPOUNDS | SIGA TECHNOLOGIES, INC., (US) | 2014-10-09 | — | — | US | disclosed |
| US-8802714-B2 | Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases | SIGA TECHNOLOGIES, INC. (US) | 2014-08-12 | — | — | US | disclosed |
| US-8791110-B2 | Anti-arenaviral compounds | SIGA TECHNOLOGIES, INC. (US) | 2014-07-29 | — | — | US | disclosed |
| US-20130345278-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF ORTHOPOXVIRUS INFECTIONS AND ASSOCIATED DISEASES | SIGA TECHNOLOGIES, INC. (US) | 2013-12-26 | — | — | US | disclosed |
| US-8530509-B2 | Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases | SIGA TECHNOLOGIES, INC. (US) | 2013-09-10 | — | — | US | disclosed |
| US-8518951-B2 | Anti-arenaviral compounds | SIGA TECHNOLOGIES, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| EP-2148860-A1 | CHEMICALS, COMPOSITIONS, AND METHODS FOR TREATMENT AND PREVENTION OF ORTHOPOXVIRUS INFECTIONS AND ASSOCIATED DISEASES | SIGA TECHNOLOGIES, INC. (US) | 2010-02-03 | — | — | EP | disclosed |
| US-20090180980-A1 | Anti-Arenaviral Compunds | SIGA TECHNOLOGIES, INC. (US) | 2009-07-16 | — | — | US | disclosed |
| WO-2008130348-A1 | CHEMICALS, COMPOSITIONS, AND METHODS FOR TREATMENT AND PREVENTION OF ORTHOPOXVIRUS INFECTIONS AND ASSOCIATED DISEASES | SIGA TECHNOLOGIES, INC. (US) | 2008-10-30 | — | — | WO | disclosed |
| EP-1984379-A2 | ANTI-ARENAVIRAL COMPOUNDS | SIGA TECHNOLOGIES, INC. (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2008079159-A2 | CHEMICALS, COMPOSITIONS, AND METHODS FOR TREATMENT AND PREVENTION OF ORTHOPOXVIRUS INFECTIONS AND ASSOCIATED DISEASES | SIGA TECHNOLOGIES, INC. (US) | 2008-07-03 | — | — | WO | disclosed |
| US-20080103181-A9 | Compounds, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases | SIGA TECHNOLOGIES, INC. (US) | 2008-05-01 | — | — | US | disclosed |
| US-20080004452-A1 | Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases | SIGA TECHNOLOGIES, INC. (US) | 2008-01-03 | — | — | US | disclosed |
| US-20070287735-A1 | Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases | SIGA TECHNOLOGIES, INC. (US) | 2007-12-13 | — | — | US | disclosed |
| WO-2007120374-A2 | ANTI-ARENAVIRAL COMPOUNDS | SIGA TECHNOLOGIES, INC. (US) | 2007-10-25 | — | — | WO | disclosed |
| US-20060235051-A1 | Compounds, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases | SIGA TECHNOLOGIES, INC. (US) | 2006-10-19 | — | — | US | disclosed |