Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1134961 | 0.86 | LMNA (0.59) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11263672 | 0.85 | LMNA (0.60) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL20037664 | 0.84 | ALDH1A1 (0.57) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL12302076 | 0.84 | KDM4E (0.67) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL3407381 | 0.83 | RAB9A (0.65) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL8288231 | 0.83 | RAB9A (0.65) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL30074610 | 0.82 | ALDH1A1 (0.56) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL21531028 | 0.82 | EPHX2 (0.58) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL30074558 | 0.82 | EPHX2 (0.58) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL30074628 | 0.82 | ALDH1A1 (0.56) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10550073-B2 | Benzamide derivative | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) | 2020-02-04 | — | — | US | disclosed |
| EP-3357916-A1 | BENZAMIDE DERIVATIVE | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2018-08-08 | — | — | EP | disclosed |
| EP-1562589-B1 | DIAMINOTRIAZOLES USEFUL AS INHIBITORS OF PROTEIN KINASES | VERTEX PHARMA (US) | 2009-01-07 | — | — | EP | disclosed |
| CN-1738615-A | Diaminotriazoles as inhibitors of protein kinases | VERTEX PHARMA (US) | 2006-02-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10550073-B2 | Benzamide derivative | CYP3A5, ABCB1, CYP2D6 | RAB9A 1551/4885SMN1; SMN2 2610/4885NPC1 731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.