Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044992 | 0.84 | ALDH1A1 (0.54) | ALDH1A1CYP2D6TSHRKDM4ETDP1 | |
| SCHEMBL31620999 | 0.83 | CYP2D6 (0.50) | ALDH1A1CYP2D6TSHRKDM4ETDP1 | |
| SCHEMBL11385195 | 0.81 | HTR1A (0.52) | ALDH1A1KDM4ESMN1; SMN2HTR1AHTR2A | |
| SCHEMBL6442660 | 0.80 | LMNA (0.51) | ALDH1A1CYP2D6TSHRKDM4ETDP1 | |
| SCHEMBL3534600 | 0.80 | LMNA (0.51) | ALDH1A1CYP2D6TSHRKDM4ETDP1 | |
| SCHEMBL7315768 | 0.79 | ALDH1A1 (0.64) | ALDH1A1CYP2D6KDM4ETDP1POLB | |
| SCHEMBL3531517 | 0.78 | SMN1; SMN2 (0.63) | ALDH1A1CYP2D6TSHRKDM4ETDP1 | |
| SCHEMBL4047895 | 0.78 | KDM4E (0.53) | ALDH1A1CYP2D6TSHRKDM4ETDP1 | |
| SCHEMBL6447779 | 0.78 | SMN1; SMN2 (0.63) | ALDH1A1CYP2D6TSHRKDM4ETDP1 | |
| SCHEMBL23965931 | 0.78 | CYP2D6 (0.53) | ALDH1A1CYP2D6TSHRKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103719-A1 | SUBSTITUTED 4-(INDOL-3-YL)QUINAZOLINES AND USE AND PRODUCTION THEREOF | FREIE UNIVERSITÄT BERLIN (DE) | 2009-08-27 | — | — | WO | disclosed |