SCHEMBL4043773

SCHEMBL4043773

CCCCC(CC)Cc1cc2c(nnn2CN)c(CC(CC)CCCC)c1C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14332180 0.91 ALDH1A1 (0.32) ALDH1A1TDP1
SCHEMBL28935093 0.87 ALDH1A1 (0.31) ALDH1A1TDP1
SCHEMBL28935876 0.84 CRHR1 (0.35) ALDH1A1TDP1
SCHEMBL6933331 0.82 GRM2 (0.35) ALDH1A1TDP1
SCHEMBL30014300 0.81 GRM2 (0.34) ALDH1A1TDP1
SCHEMBL5162819 0.81 GRM2 (0.34) ALDH1A1TDP1
SCHEMBL28495537 0.80 GRM2 (0.32) ALDH1A1TDP1
SCHEMBL28573878 0.78 GRM2 (0.43) ALDH1A1TDP1
SCHEMBL28225062 0.76 SLC9A1 (0.33) ALDH1A1TDP1
SCHEMBL29156385 0.71 SLC9A1 (0.33) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3234952-A1 LAYERED STRUCTURE WITH COPPER PASSIVATOR Borealis AG (AT) 2017-10-25 EP claimed
WO-2016096354-A1 LAYERED STRUCTURE WITH COPPER PASSIVATOR BOREALIS AG (AT) 2016-06-23 WO claimed
EP-3391386-A1 CABLE COMPRISING A FOAMED LAYER COMPRISING A POLYOLEFIN POLYMER AND A BLOWING AGENT Borealis AG (AT) 2018-10-24 EP disclosed
WO-2017102341-A1 CABLE COMPRISING A FOAMED LAYER COMPRISING A POLYOLEFIN POLYMER AND A BLOWING AGENT BOREALIS AG (AT) 2017-06-22 WO disclosed
EP-2066771-A2 LUBRICATING COMPOSITION THE LUBRIZOL CORPORATION (US) 2009-06-10 EP disclosed
WO-2008027883-A2 LUBRICATING COMPOSITION THE LUBRIZOL CORPORATION (US) 2008-03-06 WO disclosed