Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035976 | 0.71 | TBXA2R (0.36) | PPARGPPARDPPARAKDM4EMAPT | |
| SCHEMBL28827495 | 0.70 | PPARG (0.40) | PPARGPPARDPPARAKDM4EMAPT | |
| SCHEMBL4049019 | 0.70 | PDE4A (0.39) | PPARGPPARDPPARAKDM4EMAPT | |
| SCHEMBL246438 | 0.68 | KDM4E (0.53) | PPARGPPARDPPARAKDM4EMAPT | |
| SCHEMBL28639731 | 0.66 | KDM4E (0.52) | PPARGPPARDPPARAKDM4EMAPT | |
| Ammonia Solution, Strong SCHEMBL27626967 | 0.66 | KDM4E (0.52) | PPARGPPARDPPARAKDM4EMAPT | |
| SCHEMBL3748518 | 0.65 | KDM4E (0.50) | PPARGPPARDPPARAKDM4EMAPT | |
| SCHEMBL6175188 | 0.64 | PPARG (0.52) | PPARGPPARDPPARAKDM4EMAPT | |
| SCHEMBL19456402 | 0.63 | CRHBP (0.35) | PPARGPPARDPPARAKDM4EMAPT | |
| SCHEMBL10762626 | 0.63 | GABRA1 (0.43) | PPARGPPARDPPARAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323716-B1 | PROMOTERS FOR THE PROLIFERATION AND DIFFERENTIATION OF STEM CELLS AND/OR NEURON PRECURSOR CELLS | TAKEDA PHARMACEUTICAL (JP) | 2009-01-14 | — | — | EP | disclosed |