Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.40 |
| ▸ | MMP14 | P50281 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455362 | 0.90 | L3MBTL1 (0.53) | L3MBTL1CCR1CCR8HIF1AKDM4E | |
| SCHEMBL13625120 | 0.87 | NPC1 (0.45) | L3MBTL1CCR1CCR8HIF1AKDM4E | |
| SCHEMBL13625137 | 0.84 | L3MBTL1 (0.44) | L3MBTL1CCR1CCR8HIF1AKDM4E | |
| SCHEMBL13625111 | 0.83 | KDM4E (0.44) | L3MBTL1CCR1CCR8HIF1AKDM4E | |
| SCHEMBL13625108 | 0.82 | KMT2A (0.44) | L3MBTL1CCR1CCR8HIF1AKDM4E | |
| SCHEMBL4457946 | 0.81 | L3MBTL1 (0.47) | L3MBTL1CCR1CCR8HIF1AKDM4E | |
| SCHEMBL13625109 | 0.80 | PDE4A (0.46) | L3MBTL1CCR1CCR8KDM4EMAPT | |
| SCHEMBL13625126 | 0.80 | HSD11B1 (0.45) | L3MBTL1CCR1CCR8HIF1AKDM4E | |
| SCHEMBL13625138 | 0.80 | HIF1A (0.41) | L3MBTL1CCR1CCR8HIF1AKDM4E | |
| SCHEMBL4036371 | 0.80 | KMT2A (0.57) | L3MBTL1CCR1CCR8HIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101611009-A | Quinoline derivatives | CHRONOGEN INC (US) | 2009-12-23 | — | — | CN | disclosed |
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | disclosed |