Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15226066 | 0.75 | ALDH1A1 (0.47) | ABCB1CHEK1HTR7ABCC1ALDH1A1 | |
| SCHEMBL28334181 | 0.75 | CA12 (0.39) | ALDH1A1KMT2A | |
| SCHEMBL12312144 | 0.72 | PDGFRB (0.57) | ABCB1HTR7ALDH1A1NPC1RAB9A | |
| SCHEMBL4516680 | 0.72 | ALDH1A1 (0.43) | ABCB1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1663978 | 0.72 | ALDH1A1 (0.54) | ABCB1HTR7ALDH1A1NPC1RAB9A | |
| SCHEMBL1307865 | 0.69 | ABCB1 (0.52) | ABCB1HTR7ABCC1NPC1RAB9A | |
| SCHEMBL1299335 | 0.69 | SMN1; SMN2 (0.50) | ABCB1CHEK1HTR7ABCC1ALDH1A1 | |
| SCHEMBL28874514 | 0.69 | ALOX5 (0.57) | ABCB1HTR7ABCC1ALDH1A1NPC1 | |
| SCHEMBL4330380 | 0.69 | MAPT (0.56) | ABCB1HTR7ALDH1A1NPC1RAB9A | |
| SCHEMBL1308130 | 0.68 | ABCB1 (0.58) | ABCB1ABCC1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066632-B1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARM CORP (KR) | 2013-09-04 | — | — | EP | disclosed |
| EP-2066632-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | Chong Kun Dang Pharmaceutical Corp. (KR) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008038955-A1 | BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-04-03 | — | — | WO | disclosed |