SCHEMBL28334181

SCHEMBL28334181

COc1ccc(-c2[c]cc(OC)c(OC)c2OC)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TUBB4A P04350 7/20 0.39
TUBB P07437 7/20 0.39
TUBA3C P0DPH7 7/20 0.39
TUBA1B P68363 7/20 0.39
TUBA4A P68366 7/20 0.39
TUBB4B P68371 7/20 0.39
TUBB3 Q13509 7/20 0.39
TUBB2A Q13885 7/20 0.39
TUBB8 Q3ZCM7 7/20 0.39
TUBA3E Q6PEY2 7/20 0.39
TUBA1A Q71U36 7/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14775511 0.84 LMNA (0.36) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL7699767 0.84 KDM4E (0.39) CA12CA1CA2CA7CA9
SCHEMBL9509766 0.81 TUBB4A (0.43) ALDH1A1MEN1KMT2ATUBB4ATUBB
SCHEMBL7874401 0.80 SMN1; SMN2 (0.42) ALDH1A1IDO1TDO2
SCHEMBL4024400 0.79 IDO1 (0.40) CA12CA1CA2CA7CA9
SCHEMBL9738424 0.78 ACHE (0.43) CA12CA1CA2CA9ALDH1A1
SCHEMBL9538022 0.77 MAOB (0.44) ALDH1A1MEN1KMT2AFYN
SCHEMBL27688829 0.76 TUBB4A (0.41) ALDH1A1MEN1KMT2ATUBB4ATUBB
SCHEMBL4044331 0.75 ABCB1 (0.42) ALDH1A1KMT2A
SCHEMBL9044073 0.74 MAOB (0.44) ALDH1A1MEN1KMT2AFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110526805-A A kind of fluorine substituted diphenylamine ethane derivative and preparation method and application SHANGHAI INST TECH 2019-12-03 CN disclosed