Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.54 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046869 | 0.90 | CTSK (0.60) | CTSKCTSSHPGDSCTSBCTSL | |
| SCHEMBL4045501 | 0.90 | CTSK (0.53) | CTSKCTSSHPGDSCTSBCTSL | |
| SCHEMBL4041020 | 0.88 | CTSK (0.54) | CTSKCTSSHPGDSCTSBCTSL | |
| SCHEMBL4046427 | 0.88 | CTSK (0.58) | CTSKCTSSCTSLCCR1 | |
| SCHEMBL4046312 | 0.87 | CTSK (0.52) | CTSKCTSSHPGDSCTSBCTSL | |
| SCHEMBL4046824 | 0.87 | CTSK (0.70) | CTSKCTSSCTSLCCR1 | |
| SCHEMBL4040326 | 0.87 | CTSK (0.56) | CTSKCTSSCTSLCCR1 | |
| SCHEMBL4044579 | 0.87 | CTSK (0.71) | CTSKCTSSCTSBCTSLCCR1 | |
| SCHEMBL4047026 | 0.86 | CTSK (0.60) | CTSKCTSSCTSL | |
| SCHEMBL4043168 | 0.86 | CTSK (0.48) | CTSKCTSSHPGDSCTSBCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |