Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 9/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | C1R | P00736 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052221 | 0.77 | DCUN1D1 (0.46) | NOTUMTRPA1PARP1 | |
| SCHEMBL1119527 | 0.72 | HSD11B1 (0.41) | NOTUMHSD11B1TRPA1TRPM8TRPV1 | |
| SCHEMBL28226382 | 0.70 | IDO1 (0.56) | NOTUMHSD11B1TRPA1TRPM8TRPV1 | |
| SCHEMBL723099 | 0.70 | HSD11B1 (0.46) | NOTUMHSD11B1TRPA1TRPM8TRPV1 | |
| SCHEMBL197671 | 0.70 | HSD11B1 (0.56) | NOTUMHSD11B1TRPA1TRPM8TRPV1 | |
| SCHEMBL10671205 | 0.69 | NOTUM (0.54) | NOTUMHSD11B1TRPA1PARP1NPY5R | |
| SCHEMBL4043039 | 0.69 | NOTUM (0.46) | NOTUMHSD11B1TRPA1TRPM8TRPV1 | |
| SCHEMBL9831253 | 0.69 | NOTUM (0.46) | NOTUMTRPA1TRPM8TRPV1 | |
| SCHEMBL4050332 | 0.68 | GFER (0.46) | NOTUMTRPV1PARP1 | |
| Hydrochloric Acid SCHEMBL29010139 | 0.68 | HSD11B1 (0.54) | NOTUMHSD11B1TRPA1TRPM8TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589096-B2 | Azole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-09-15 | — | — | US | disclosed |
| EP-1566384-B1 | NOVEL AZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2009-06-17 | — | — | EP | disclosed |
| US-20080188507-A1 | Novel azole derivatives | MSD K.K. (JP) | 2008-08-07 | — | — | US | disclosed |
| US-7365079-B2 | Azole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-04-29 | — | — | US | disclosed |
| US-20060111380-A1 | Novel azole derivatives | MSD K.K. (JP) | 2006-05-25 | — | — | US | disclosed |
| EP-1566384-A1 | NOVEL AZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188507-A1 | Novel azole derivatives | NPY1R, NPY5R, NPY2R | NOTUM 2706/4885HSD11B1 1985/4885TRPA1 2104/4885 |
| US-20060111380-A1 | Novel azole derivatives | NPY1R, NPY5R, NPY2R | NOTUM 2436/4885HSD11B1 1657/4885TRPA1 2043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.