Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044130 | 0.80 | PYCR1 (0.40) | BCL2A1SLC6A3SLC6A4OPRM1 | |
| SCHEMBL1327427 | 0.73 | BCL2A1 (0.43) | BCL2A1SLC6A3SLC6A4 | |
| SCHEMBL1326713 | 0.73 | BCL2A1 (0.46) | BCL2A1SLC6A3SLC6A4OPRM1KDR | |
| SCHEMBL22012424 | 0.73 | HTR2A (0.35) | BCL2A1HTR2AHTR2C | |
| SCHEMBL493690 | 0.73 | AOC3 (0.38) | HTR2ASLC6A3SLC6A4 | |
| SCHEMBL1326522 | 0.73 | SLC6A4 (0.38) | HTR2AHTR2CSLC6A3SLC6A4OPRM1 | |
| SCHEMBL22012419 | 0.73 | ALDH1A1 (0.45) | CHRNA7 | |
| SCHEMBL17900515 | 0.72 | GAA (0.47) | HTR2ASLC6A3SLC6A4OPRM1KDR | |
| SCHEMBL13903208 | 0.72 | GAA (0.47) | HTR2ASLC6A3SLC6A4OPRM1KDR | |
| SCHEMBL643245 | 0.72 | IDO1 (0.38) | HTR2ASLC6A3SLC6A4OPRM1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103478-A1 | PYRIDONE AND PYRIDAZINONE DERIVATIVES AS MCH ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |